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. 2021 Mar 8;9(3):373–383. doi: 10.14218/JCTH.2021.00050

Fig. 8. Proposed mechanisms of icaritin on lipid accumulation.

Fig. 8

Icaritin attenuates lipid accumulation by enhancing energy expenditure and regulating autophagy. These effects were induced by activating the LKB1/AMPK/ACC pathway. Abbreviations: ACC, Acetyl-CoA carboxylase; AMPK, adenosine 5′-monophosphate-activated protein kinase; LKB1, liver kinase B1.