. 2021 Mar 31;9(3):345–352. doi: 10.14218/JCTH.2020.00124

Table 3. Performance of the Nanjing criteria and simplified Nanjing criteria for the diagnosis of PA-HSOS.

Diagnostic criteria	Reference standard				Sensitivity, % (95% CI)	Specificity, % (95% CI)	PPV, %)(95% CI)	NPV, % (95% CI)	Positive likelihood ratio	Negative likelihood ratio	Overall accuracy
Diagnostic criteria	TP	FP	TN	FN	Sensitivity, % (95% CI)	Specificity, % (95% CI)	PPV, %)(95% CI)	NPV, % (95% CI)	Positive likelihood ratio	Negative likelihood ratio	Overall accuracy
Nanjing criteria (i+ii+iii+iv)	82	0	327	4	95.35 (90.81–99.89)	100	100	98.79 (97.61–99.97)	—	0.046	99.03
Simplified Nanjing criteria (ii+iii+iv)	83	12	315	3	96.51 (92.55–100)	96.33 (94.28–98.38)	87.37 (80.57–94.17)	99.06 (97.99–100)	25.98	0.036	96.37

i. History of ingesting PA-containing plants; ii. Clinical manifestation; iii. Abnormal liver function (abnormal liver function: ALT >40 U/L, AST >40 U/L or serum TBil >17.1 µmol/L); iv. Imaging performance. TP, true positive; FP, false positive; TN, true negative; FN, false negative.