Table 1. Characteristics of the ACLF patients and HCs at the time of hospital admission.
| Indictor | ACLF patients, n=30 | HCs, n=30 | pa |
|---|---|---|---|
| Age in years | 53.2±9.2 | 50.5±11.2 | 0.595 |
| Female, n (%) | 12 (40.0) | 13 (43.3) | 0.962 |
| BMI in kg/m2 | 23.6±3.6 | 25.6±2.9 | 0.496 |
| ALT in U/L | 121.4±90.8 | 33.3±11.1 | <0.001* |
| AST in U/L | 129.6±41.7 | 24.3±6.3 | <0.001* |
| TBIL in µmol/L | 410.4±143.7 | 17.7±5.8 | <0.001* |
| PTA, % | 28.5±4.2 | 120.0±5.1 | <0.001* |
| INR | 2.1±0.3 | 0.9±0.2 | <0.001* |
| Albumin in g/L | 29.1±3.5 | 39.5±1.6 | <0.001* |
| Urea in mmol/L | 5.2±1.4 | 5.4±1.1 | 0.474 |
| Creatinine in µmol/L | 70.3±6.3 | 67.1±3.1 | 0.133 |
| MELD score | 23.5±5.5 | – | – |
*p<0.05. ap-values were acquired by chi-square test or t-test. ACLF, acute-on-chronic liver failure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; HCs, healthy controls; INR, international normalized ratio; MELD, model for end-stage liver disease; PTA, prothrombin activity; TBIL, total bilirubin.