Table 5.
Secondary outcomes
Standard (n=29) n (%)* |
Restrictive (n=29) n (%)* |
Odds ratio (95% CI)† | P Value† | |
Mortality | 6 (21) | 7 (24) | 0.82 (0.24 to 2.83) | 0.75 |
Severe ultrasound abnormality | 5 (17) | 5 (17) | 1.00 (0.26 to 3.91) | 1 |
Grade 3/4 IVH | 5 (17) | 2 (7) | 3.06 (0.51 to 18.41) | 0.22 |
PVL | 2 (7) | 2 (7) | 1.04 (0.13 to 8.37) | 0.97 |
Any ultrasound abnormality | 16 (55) | 13 (45) | 1.51 (0.54 to 4.26) | 0.43 |
NEC | 1 (3) | 4 (14) | 0.22 (0.02 to 2.13) | 0.19 |
SIP | 3 (10) | 3 (10) | 1.00 (0.18 to 5.42) | 1 |
BPD‡ | 17 (74) | 14 (64) | 1.87 (0.45 to 7.68) | 0.39 |
Duration of inotrope (hours) | 17.8 (7.5–30.6)§¶ | 13.7 (6.1–24.5)§** | 1.46 (0.84 to 2.56)†† | 0.18 |
Any intervention | 11 (38) | 19 (66) | 0.32 (0.11 to 0.94) | 0.038 |
*Unless otherwise stated.
†From logistic regression analysis unless otherwise stated.
‡Of those who had survived to 36 weeks.
§Median (IQR).
¶n=21 in the standard group.
**n=22 in the restricted group.
††Ratio of geometric means as the duration variable was log-transformed.
BPD, bronchopulomary dysplasia; IVH, intraventricular haemorrhage; NEC, necrotising enetrocolitis; PVL, periventricular leucomalacia; SIP, spontaneous intestinal perforation.