Table I.
Pt | Sub‐type | Karyotype | Age at diagnosis (years) | Gender | Disease status at biopsy | MRD Risk† | Treatment protocol |
---|---|---|---|---|---|---|---|
1 | c‐ALL | Hyperdiploidy | 7 | M | D | High | UKALL 2003 |
2 | Pre B | t(12;21) | 2 | F | D | Low | UKALL 2003 |
3 | Pre B | −1 | 2 | F | D | Low | UKALL 2003 |
4 | Pre B | t(9;22) | 15 | M | D | Low | UKALL 2011 |
5 | Pre B | Hyperdiploidy | 2 | M | D | Low | UKALL 2003 |
6 | Pre B | 46XY | 9 | M | D | High | UKALL 2011 |
7 | Pre B | t(12;21) | 2 | F | D | Low | UKALL 2011 |
8 | c‐ALL | t(12;21) | 4 | M | D | ND | UKALL 2011 |
9 | Pre B | −9, +10, −18 | 2 | F | D | High | UKALL 2003 |
10 | Pre B | 46XY | 14 | F | D | Int | UKALL 2011 |
11 | Pre B | +7, −9, −Y | 3 | M | D | Low | UKALL 2011 |
12 | c‐ALL | t(12;21) | 7 | F | D | Low | UKALL 2011 |
13 | c‐ALL | +5 | 5 | F | D | Int | UKALL 2011 |
14 | Pro B | 11q23 rearr | 15 | F | D | High | UKALL 2011 |
15 | Pro B | 11q23 rearr | 17 | F | D | Int | UKALL 2011 |
16 | Pre B | t(12;21) | 5 | M | D | Low | UKALL 2011 |
17 | Pre B | t(12;21) | 3 | M | D | Low | UKALL 2011 |
18 | Pre B | PDGFRB rearr, −12p | 8 | F | D | High | UKALL 2011 |
19 | Pre B | t(1;19) | 12 | M | D | Low | UKALL 2011 |
20 | c‐ALL | +5 | 17 | M | D | Low | UKALL 2011 |
21 | T‐ALL | +4, +9 | 15 | M | D | High | UKALL 2003 |
22 | T‐ALL | t(11;14) | 2 | M | R | Low | UKALL 2003 |
23 | T‐ALL | 46XY | 17 | M | D | High | UKALL 2003 |
24 | T‐ALL | −3, −6, −11, +1 | 2 | F | D | ND | UKALL 2011 |
25 | T‐ALL | t(1;14) | 3 | M | D | Int | UKALL 2011 |
26 | T‐ALL | 46XY | 6 | M | D | Low | UKALL 2011 |
27 | T‐ALL | −4, −9 | 9 | M | D | Low | UKALL 2011 |
28 | T‐ALL | 46XY | 7 | M | D | Int | UKALL 2011 |
29 | T‐ALL | 21q22 rearr | 3 | M | D | ND | UKALL 2011 |
30 | T‐ALL | +7, +9, +14, +mar | 4 | M | D | Low | UKALL 2011 |
31 | T‐ALL | +ABL1 | 10 | M | D | Int | UKALL 2011 |
D, diagnosis; Int, intermediate; ND, not determined; R, relapse. ALL, acute lymphoblastic leukaemia; c ‐ALL, common ALL; pre B, B‐cell ALL; pro B, B‐cell ALL; T‐ALL, T‐cell ALL. UKALL 2003; UKALL 2011.
MRD risk status at day 29 for UKALL 2003 and at week 14 for UKALL 2011.