Table 4.

Weighted arithmetic mean, minimum and maximum proportion of resistance (%R or %R + I) and weighted standard deviation in E. coli for the target antimicrobials on each continent

Antibiotic	Continent	Number of papers	Number of isolates	Weighted arithmetic mean % of resistance	Minimum resistance % observed	Maximum resistance % observed	Weighted standard deviation
3GC	Asia	5	599	20	0	33.3	11.6
3GC	Europe	13	9,350	6.5	0.2	71.4	10.4
3GC	North America	4	4,444	13.3	1.8	22	3.2
3GC	Oceania	1	855	8.4	8.4	8.4	NA
Aminopenicillins	Africa	1	164	70.1	70.1	70.1	NA
Aminopenicillins	Asia	4	408	45	30	59.1	11.2
Aminopenicillins	Europe	12	8,716	33.1	12.1	100	19
Aminopenicillins	North America	8	12,486	37.2	8.8	62.9	10
Aminopenicillins	Oceania	2	1,013	37.8	37.2	41	1.4
Amox/Clav	Africa	1	163	58.3	58.3	58.3	NA
Amox/Clav	Asia	3	294	15.8	2.6	30.7	13.4
Amox/Clav	Europe	12	13,382	18.6	0	100	17.3
Amox/Clav	North America	7	12,408	22.2	2.7	40	11.4
Amox/Clav	Oceania	3	2,121	35.1	11.8	67.2	26.6
Fluoroquinolones	Africa	1	167	16.2	16.2	16.2	NA
Fluoroquinolones	Asia	6	703	45	5.3	92.5	31.4
Fluoroquinolones	Europe	14	8,820	8.3	2.1	39.3	9.6
Fluoroquinolones	North America	7	12,405	10.5	1.8	19.6	5.8
Fluoroquinolones	Oceania	4	2,267	4.4	2.3	8	2.3
Nitrofurantoin	Europe	2	2,056	1.1	1	1.6	0.2
Sulfa/TMP	Africa	1	166	24.7	24.7	24.7	NA
Sulfa/TMP	Asia	5	563	52.4	25	77.5	21.4
Sulfa/TMP	Europe	12	14,481	11.5	4.3	61.2	9
Sulfa/TMP	North America	6	12,030	10.1	0	17.9	5
Sulfa/TMP	Oceania	2	1,264	8.9	8	15	2.3

NA: Standard deviation cannot be calculated because only one study is included.