Fig. 2.

Predictive performance of DLRS for DMFS. (a) and (b) are time-dependent ROC curves for one year, two years and three years of the primary cohort (n = 170) and external validation cohort (n = 65). (c) and (d) are K-M curves for stratifying high- and low-risk patients of DM of the primary cohort (P < 0·0001, log-rank test) and external validation cohort (P < 0·0001, log-rank test). The numbers of patients at risk for each time step are shown in the bottom. DLRS deep learning risk signature; DMFS distant metastasis free survival; ROC receiver operating characteristic; AUC area under receiver operating characteristic curve.