Table 1.

Inhibition rate (%) by l-menthol of binding of a ligand against a specific molecule (a) Ligands of which inhibition rate were more than 20 % (b) Ligands of which inhibition rate were more than 10 % and less than 20 %.

Molecule of interest	Radioactive isotope-labeled ligand	Preparation containing molecule of interest	Inhibition by l-Menthol (%)	Inhibition by a positive control substance (%)	Positive control substance
Inhibition > 20 %
Dopamine D4.2 receptor (Human)	[3H]-Spiperone	Human recombinant	28.19	100	Haloperidol
Ca channel (Type L, Phenylalkylamine)	[3H]-(-)-Desmethoxyverapamil	Rat cerebral cortex	24.78	100	(±)-Methoxyverapamil hydrochloride
Bombesin receptor (Non-selective)	[125I]-Bombesin	Rat whole brain	21.87	98.81	Bombesin acetate hydrate
Adenosine A2a receptor (Human)	[3H]-CGS21680	Human recombinant	21.62	99.12	CGS21680 hydrochloride
Histamine H2 receptor (Human)	[3H]-Tiotidine	Human recombinant	21.17	100	Cimetidine
GABA A receptor (Picrotoxin site)	[3H]-EBOB	Rat cerebral cortex	20.9	94.33	Picrotoxin
Dopamine transporter (Human)	[3H]-WIN35,428	Human recombinant	20.67	99.41	GBR12909 dihydrochloride
(b) 20% > Inhibition > 10 %
Angiotensin AT1 receptor (Human)	[125I]-Angiotensin II (Sar 1, Ile 8)	Human recombinant	16.92	100	Angiotensin II human
Na Channel	[3H]-Batrachotoxinin A 20-alpha-Benzoate	Rat whole brain	14.04	99.46	Dibucaine hydrochloride
Vasopressin V2 receptor (Human)	[3H]-Vasopressin, 8-L-Arginine	Human recombinant	13.53	98.02	[Arg 8]-Vasopressin
Leukotriene B4 receptor	[3H]-Leukotriene B4	Guinea pig lung	11.63	92.71	Leukotriene B4
α2A-Adrenergic receptor (Human)	[3H]-Rauwolscine hydrochloride	Human recombinant	11.34	100	Rauwolscine hydrochloride
GABA transporter	gamma-[3H]-Aminobutyric Acid, ([3H]GABA)	Rat cerebral cortex	10.09	100	γ-Aminobutyric acid (GABA)