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Meiosis I and meiosis II segregation errors and their age dependency in human oocytes. (A) Chromosome segregation patterns in meiosis I and meiosis II. (B) The U‐curve of aneuploidy in human oocytes (dotted red line) is a compilation of all three chromosome missegregation events—MI NDJ (blue), PSSC (orange), and RS (yellow)—and acts in an age dependent manner. MI NDJ, MI non‐disjunction; PSSC, premature separation of sister chromatids; RS, reverse segregation
