Table 5.
Day 14 |
Day 28 |
Day 42 |
|||||||
---|---|---|---|---|---|---|---|---|---|
AMR genes2 | NC | CuSO4, mg/kg | Cu2O, mg/kg | NC | CuSO4, mg/kg | Cu2O, mg/kg | NC | CuSO4, mg/kg | Cu2O, mg/kg |
Enterococcus spp. | |||||||||
vanC1 | 70% | 70% | 100% | 30% | 20% | 10% | 100% | 100% | 70% |
vanC2 | 60% | 70% | 100% | 90% | 90% | 80% | 100% | 100% | 100% |
tetM | 100% | 90% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
ermB | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
ESBL | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
OXA-48 | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
tcrB | 90% | 80% | 80% | 80% | 60% | 90% | 100% | 100% | 100% |
czcA | 10% | 10% | 0% | 0% | 10% | 0% | 50% | 40% | 0% |
E. coli | |||||||||
vanC1 | 20% | 0% | 0% | 0% | 20% | 0% | 0% | 0% | 0% |
vanC2 | 20% | 0% | 30% | 0% | 10% | 0% | 0% | 0% | 0% |
tetM | 89% | 10% | 0% | 89% | 90% | 86% | 0% | 0% | 0% |
ermB | 78% | 100% | 10% | 78% | 80% | 100% | 50% | 70% | 20% |
ESBL | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
OXA-48 | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
tcrB | 0% | 0% | 0% | 0% | 10% | 0% | 70% | 20% | 40% |
czcA | 100% | 50% | 50% | 78% | 100% | 43% | 0% | 0% | 0% |
Data are means of 10 replicates per treatment.
Antimicrobial resistance genes: vancomycin (vanC1, and vanC2); tetracycline (tetM); erythromycin (ermB); penicillin, aminopenicillin and last generation cephalosporine (ESBL); imipenem (OXA-48); Cu (tcrB); Zinc (czcA).