Table 2.

Results of longitudinal linear models on continuous clinical outcomes. Pairwise differences between course of cannabis use classes are shown at baseline, 12-month follow-up, and the change between baseline and 12 months. Overall joint tests were also computed for each set of pairwise comparisons.

Pairwise differences	GAF Symptoms			GAF SF			GAF OC
	b	95% CI	p	b	95% CI	p	b	95% CI	p
At baseline
Reduced vs persistent	1.14	(−2.05,4.33)	0.485	0.45	(−2.25, 3.14)	0.746	0.58	(−3.72, 4.87)	0.792
Reduced vs no use	−1.93	(−4.95,1.09)	0.211	0.55	(−2.01, 3.10)	0.675	−2.10	(−6.16,1.96)	0.311
Persistent vs no use	−3.06	(−5.45, −0.68)	0.012	0.10	(−1.92, 2.12)	0.921	−2.68	(−5.90, 0.54)	0.103
At 12 months
Reduced vs persistent	5.33	(1.38, 9.29)	0.008	0.41	(−2.85, 3.68)	0.803	−0.29	(−5.56,4.97)	0.914
Reduced vs no use	1.95	(−1.81,5.70)	0.310	1.20	(−1.90, 4.30)	0.448	−1.94	(−6.93, 3.06)	0.447
Persistent vs no use	−3.39	(−6.26, −0.52)	0.021	0.79	(−1.59, 3.16)	0.517	−1.65	(−5.48, 2.19)	0.400
Change from BLto12 months
Reduced vs persistent	4.20	(−0.69, 9.09)	0.093	−0.03	(−3.89,3.83)	0.988	−0.87	(−7.32, 5.59)	0.792
Reduced vs no use	3.87	(−0.74,8.49)	0.100	0.65	(−2.99, 4.30)	0.725	0.16	(−5.93, 6.25)	0.959
Persistent vs no use	−0.32	(−3.89, 3.24)	0.858	0.68	(−2.13, 3.50)	0.634	1.03	(−3.68, 5.74)	0.668
	GAF Symptoms			GAF SF			GAF OC
Overall effects	F	df	p	F	df	p	F	df	p
Overall test at baseline	3.28	(2,3771)	0.038	0.09	(2,3763)	0.915	1.46	(2,3754)	0.232
Overall test at 12 months	4.35	(2,3771)	0.013	0.38	(2,3763)	0.683	0.49	(2,3754)	0.612
Overall test of change (12 m-BL)	1.61	(2,3771)	0.200	0.14	(2,3763)	0.872	0.10	(2,3754)	0.909