Table 2.
Changes on hemodynamic and echocardiographic parameters before and after TAVR (n = 32)
| Variables | Pre-TAVR | Post-TAVR | P value |
|---|---|---|---|
| Heart rate (bpm) | 66 (61–76.5) | 70.5 (61–79.5) | 0.67 |
| Systolic blood pressure (mmHg) | 120 (110–127) | 118 (110–129.5) | 0.33 |
| Diastolic blood pressure (mmHg) | 64.5 (57.5–68.5) | 60.5 (48.5–71.5) | 0.40 |
| Peak aortic velocity (Vmax) (m/s) | 4.6 ± 0.8 | 2.3 ± 0.4 | < 0.001 |
| Mean transaortic PG (m/s) | 53 ± 21 | 12 ± 4 | < 0.001 |
| AVAI or EOAI (cm2/m2) | 0.5 ± 0.1 | 1.1 ± 0.2 | < 0.001 |
| Paravalvular leak severity I/II/III/IV, n (%) | – | 24 (75)/4 (13)/0/0 | – |
| LVEDD (mm) | 46.7 (43.0–50.0) | 46.0 (42.5–49.0) | 0.99 |
| LVESD (mm) | 28.0 (24.5–34.5) | 28.5 (25.0–32.0) | 0.71 |
| LVEF (%) | 61 (54–70) | 64 (56–70) | 0.010 |
| Transmitral peak E/A ratio | 0.70 (0.56–0.97) | 0.70 (0.62–0.91) | 0.058 |
| E/e′ ratio | 13.1 ± 4.8 | 14.0 ± 4.2 | 0.25 |
| LAVI (mL/m2) | 45.5 (39.7–63.0) | 44.8 (36.1–58.5) | 0.78 |
| LVMI (g/m2) | 118 (102–141) | 115 (98–145) | 0.65 |
| RWT | 0.44 (0.39–0.49) | 0.44 (0.38–0.47) | 0.63 |
Continuous variables are presented as mean ± standard deviation if normally distributed, and median (interquartile range) if not normally distributed
Categorical variables are presented as number of patients (%)
AVAI aortic valve area index; EOAI effective orifice area index; LAVI left atrial volume index; LVEDD left ventricular end-diastolic dimension; LVESD left ventricular end-systolic dimension; LVEF left ventricular ejection fraction; LVMI left ventricular mass index; PG pressure gradient; RWT relative wall thickness; TAVR transcatheter aortic valve replacement