Table 2.
Relative abundance of the 8 metabolites related to the AMH decline rate by tertiles of dairy intakea
| Dairy groups | Metabolitesb | Tertile 1 | Tertile 2 | Tertile 3 | p-trend | q-valuec |
|---|---|---|---|---|---|---|
| Total dairy | N-Acetyl-d-glucosamine | Ref | − 0.340 (− 0.678, − 0.003) | − 0.313 (− 0.656, 0.030) | 0.068 | 0.154 |
| Phosphate | Ref | − 0.435 (− 0.770, − 0.100) | − 0.433 (− 0.774, − 0.093) | 0.01 | 0.048 | |
| Valine | Ref | − 0.467 (− 0.818, − 0.116) | − 0.492 (− 0.848, − 0.135) | 0.006 | 0.048 | |
| Leucine | Ref | − 0.523 (− 0.867, − 0.180) | − 0.636 (− 0.986, − 0.287) | < 0.001 | 0.012 | |
| Isoleucine | Ref | − 0.384 (− 0.732, − 0.037) | − 0.465 (− 0.818, − 0.112) | 0.009 | 0.048 | |
| Proline | Ref | − 0.503 (− 0.850, − 0.155) | − 0.657 (− 1.01, − 0.304) | < 0.001 | 0.012 | |
| Pyroglutamic acid | Ref | − 0.289 (− 0.647, 0.069) | − 0.229 (− 0.593, 0.135) | 0.203 | 0.287 | |
| Urea | Ref | − 0.323 (− 0.680, 0.035) | − 0.319 (− 0.683, 0.044) | 0.079 | 0.154 | |
| Fermented dairy | N-Acetyl-d-glucosamine | Ref | − 0.102 (− 0.442, 0.237) | − 0.212 (− 0.554, 0.130) | 0.223 | 0.289 |
| Phosphate | Ref | − 0.166 (− 0.503, 0.171) | − 0.382 (− 0.721, − 0.042) | 0.027 | 0.081 | |
| Valine | Ref | − 0.087 (− 0.441, 0.266) | − 0.408 (− 0.764, − 0.502) | 0.022 | 0.081 | |
| Leucine | Ref | − 0.031 (− 0.382, 0.320) | − 0.388 (− 0.741, − 0.034) | 0.026 | 0.081 | |
| Isoleucine | Ref | − 0.027 (− 0.378, 0.324) | − 0.295 (− 0.648, 0.058) | 0.090 | 0.154 | |
| Proline | Ref | 0.012 (− 0.343, 0.367) | − 0.374 (− 0.731, − 0.016) | 0.032 | 0.085 | |
| Pyroglutamic acid | Ref | − 0.041 (− 0.400, 0.318) | − 0.217 (− 0.489, 0.235) | 0.483 | 0.504 | |
| Urea | Ref | − 0.013 (− 0.370, 0.345) | − 0.307 (− 0.666, 0.053) | 0.082 | 0.154 | |
| Milk | N-Acetyl-d-glucosamine | Ref | 0.128 (− 0.212, 0.468) | − 0.195 (− 0.536, 0.147) | 0.188 | 0.282 |
| Phosphate | Ref | 0.110 (− 0.231, 0.450) | − 0.220 (− 0.562, 0.122) | 0.146 | 0.233 | |
| Valine | Ref | 0.108 (− 0.253, 0.469) | − 0.033 (− 0.395, 0.330) | 0.774 | 0.774 | |
| Leucine | Ref | 0.126 (− 0.230, 0.483) | − 0.176 (− 0.534, 0.182) | 0.250 | 0.300 | |
| Isoleucine | Ref | 0.111 (− 0.244, 0.466) | − 0.110 (− 0.467, 0.246) | 0.451 | 0.504 | |
| Proline | Ref | 0.107 (− 0.254, 0.467) | − 0.190 (− 0.552, 0.172) | 0.229 | 0.289 | |
| Pyroglutamic acid | Ref | − 0.099 (− 0.458, 0.261) | − 0.310 (− 0.671, 0.051) | 0.084 | 0.154 | |
| Urea | Ref | 0.044 (− 0.319, 0.406) | − 0.115 (− 0.479, 0.249) | 0.480 | 0.504 |
aData is reported as differences in least-squares means of relative abundance of metabolites compared to the tertile 1 as the reference group after adjustment for age, BMI, energy intake, grains and legumes intakes
bMetabolites values are natural log or square root-transformed and auto-scaled
cp value corrected for multiple comparisons using Benjamini–Hochberg procedure