Table 4.

Mediation effects of dairy intakes on AMH fast decline rate through metabolites^a,b

Metabolitec	Effect of M on Yd		Indirect effectf
	Βetae (95% CIs)	p value	Beta (95% CIs)	SE
Phosphate	0.66 (0.26, 1.06)	0.001	− 0.11 (− 0.24, − 0.03)	0.059
BCAAs	0.20 (0.07, 0.33)	0.003	− 0.11 (− 0.25, − 0.02)	0.053
Proline	0.40 (0.07, 0.74)	0.019	− 0.09 (− 0.22, − 0.01)	0.051
Urea	0.31 (− 0.02, 0.65)	0.064	− 0.05 (− 0.15, 0.003)	0.042
Phosphate + BCAAs + proline	0.13 (0.05, 0.22)	0.002	− 0.12 (− 0.26, − 0.04)	0.057

AMH anti-Müllerian hormone, BCAAs Branched-chain amino acids

^aAdjusted for age and BMI at metabolomics measurement, energy intake, dietary intakes of legumes and grains (g/1000 kcal)

^bThe AMH fast decline rate was defined as yearly decline rates ≥ of 5.93% based on this variable's third tertile

^cNatural log or square root-transformed

^dEffects of mediators (metabolites) on AMH fast decline rate

^eStandardized value

^fEstimated using boot-strapping