Table 1.
Baseline patient characteristics
| SBT success N = 22 | SBT failure N = 31 | p | |
|---|---|---|---|
| Age, years | 61 (50–71) | 63 (55–63) | 0.638 |
| Female, n (%) | 10 (45) | 15 (48) | 0.999 |
| Body mass index, kg.m−2 | 24 (21–27) | 25 (20–30) | 0.609 |
| Pre-existing conditions, n (%) | |||
| Hypertension | 8 (36) | 10 (32) | 0.776 |
| Chronic left ventricle failure | 4 (18) | 8 (26) | 0.740 |
| COPD | 3 (14) | 4 (13) | 0.999 |
| SAPS 2 | 57 (47–77) | 65 (49–76) | 0.493 |
| SOFA | 10 (6–11) | 10 (7–12) | 0.756 |
| Fluid balance over last 24 h, L | − 0.6 (− 1.2–0.7) | − 0.8 (− 1.6–0.7) | 0.205 |
| Length of ICU stay, days | 5 (2–6) | 5 (2–12) | 0.570 |
| Duration of mechanical ventilation, days | 4 (2–6) | 5 (2–11) | 0.468 |
| SBT before inclusion, n | 1 (1–1) | 1 (1–1) | 0.113 |
| Main reason for intubation, n (%) | |||
| Acute respiratory failure | 13 (59) | 16 (52) | 0.779 |
| Coma | 7 (32) | 12 (39) | 0.772 |
| Shock | 1 (5) | 1 (3) | 0.999 |
| Post-surgery | 1 (5) | 2 (6) | 0.999 |
| Ventilator settings | |||
| Pressure support, cmH2O | 10 (7–10) | 12 (10–12) | < .001 |
| PEEP, cmH2O | 5 (5–6) | 6 (5–6) | 0.076 |
| Expired tidal volume, ml.kg−1 IBW | 7 (7–9) | 7 (6–7) | 0.053 |
SBT, spontaneous breathing trial; COPD, chronic obstructive pulmonary disease; SAPS, Simplified Acute Physiology Score; SOFA Sequential Organ Failure Assessment; ICU, intensive care unit; PEEP, positive end-expiratory pressure; IBW, ideal body weight