Fig. 5.

(A) PTMs in Neural Cell Adhesion Molecule 1 (Uniprot identifier P13595) [Gene: Ncam1]. A Byonic filter score of 300 was used. (B) Venn diagram showing co-existence of phosphorylation, N-glycosylation and O-glycosylation at the protein level; (C) Heatmap of the correlation of number of PTM sites and number of different glycans by protein. Only co-modified proteins were included (for example, row 5, column 3 means the correlation between number of N- and O-glycosites for proteins that are both N- and O-glycosylated is 0.36). (D)(E) Scatterplots of number of modified sites within proteins that contain the two PTMs. The accessions of hypermodified proteins are labeled.