Skip to main content
. 2021 Jun 21;118(25):e2026176118. doi: 10.1073/pnas.2026176118

Fig. 5.

Fig. 5.

PTH and osteolectin additively increase trabecular bone volume. (A) Representative microCT images of cortical bone in the midfemur diaphysis of male wild-type (WT) mice treated with PBS, PTH, osteolectin (Oln), or the combination of PTH plus osteolectin for 3 mo. (B–D) MicroCT analysis of the cortical bone volume/total volume (B), cortical thickness (C), and cortical bone mineral density (D) in the midfemur diaphysis of these mice. (E) Representative microCT images of trabecular bone in the distal femur metaphysis of male mice. (F–K) MicroCT analysis of the trabecular bone volume/total volume (F), trabecular number (G), trabecular thickness (H), trabecular spacing (I), trabecular connectivity density (J), and trabecular bone mineral density (K) in the distal femur metaphysis of these mice. For all experiments, n = 5 mice per group. All data represent mean ± SD. Statistical significance was assessed using one-way ANOVAs (C, F, G, and J) or two-way ANOVAs (D, H, I, and K) followed by Tukey’s multiple comparisons tests (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001).