Table 1.
Demographic and clinical data of the study participants
| BSP subjects | Healthy controls | p value | |
|---|---|---|---|
| Number of subjects | 17 | 17 | |
| Age, years | 66.6 ± 8.4 | 66.7 ± 8.3 | 0.9 |
| Sex (female/male/intersex) | 12/5/0 | 12/5/0 | 1* |
| Education, years | 9.8 ± 1.7 | 10.2 ± 1.9 | 0.6 |
| ΔWeight cotton swabs, g | 1.9 ± 0.9 | 1.8 ± 1.4 | 0.8 |
| MoCA | 29.0 ± 1.4 | 29.1 ± 1.1 | 0.7 |
| ΔTMT, s | 49.2 ± 22.7 | 56.8 ± 30.7 | 0.4 |
| DST | 16.3 ± 4.2 | 16.6 ± 2.8 | 0.5 |
| FAS | 37.6 ± 8.9 | 43.2 ± 13.5 | 0.2 |
| BSI, depression sub-score | 2.2 ± 4.5 | 1.4 ± 1.5 | 0.6 |
| BSI, anxiety sub-score | 2.6 ± 2.6 | 1.9 ± 2.1 | 0.5 |
| Disease duration of BSP, years | 9.8 ± 7.0 | ||
| BSRS total | 8.3 ± 2.7 | ||
| JRS, severity | 2.3 ± 0.8 | ||
| JRS, frequency | 2.9 ± 0.7 |
Values are mean ± standard deviation; BSP, blepharospasm; p values marked with *are based on the Fisher test; otherwise, exact Mann–Whitney U test was applied; MoCA, Montreal Cognitive Assessment (Freitas et al. 2012); ΔTMT, Difference between Trail-Making-Test part B—part A (Brown et al. 1958); DST, sum of Digit-Span-Test (de Paula et al. 2016); FAS, FAS-Test (Machado et al. 2009); BSI, Brief symptom inventory (Franke 2000); BSRS, Blepharospasm Severity Rating Scale (Defazio et al. 2015); JRS, Jankovic Rating Scale (Jankovic and Orman 1987).