Table 1.
Baseline characteristic based on NCCS compliance status stratified by HCC stages
| Baseline characteristic for early HCC patients | Early stage HCC |
Locally advanced HCC |
Metastatic HCC |
||||||
|---|---|---|---|---|---|---|---|---|---|
| noncompliant to NCCS guidelines N = 13 (10.1%) | compliant to NCCS guidelines N = 116 (89.9%) | p value | noncompliant to NCCS guidelines N = 57 (21.4%) | compliant to NCCS guidelines N = 209 (78.6%) | p value | noncompliant to NCCS guidelines N = 50 (27.3%) | compliant to NCCS guidelines N = 133 (72.7%) | p value | |
| Race, n (%) | |||||||||
| Chinese | 8 (61.54) | 65 (56.03) | 50 (87.72) | 122 (58.37) | 42 (84.00) | 90 (67.67) | |||
| Indian Malay |
1 (7.69) 2 (15.38) |
4 (03.45) 7 (06.03) |
0.2074 | 0 (0.0) 2 (3.51) |
8 (3.83) 15 (7.18) |
0.1385 | 1 (2.00) 1 (2.00) |
3 (2.26) 5 (3.76) |
0.1385 |
| Others | 2 (15.38) | 40 (34.48) | 5 (8.77) | 64 (30.62) | 6 (12.00) | 35 (26.32) | |||
| Gender, n (%) | |||||||||
| Male | 10 (76.92) | 31 (26.72) | 1.0000 | 50 (87.72) | 171 (81.82) | 0.3271 | 42 (84.00) | 117 (87.97) | 0.4699 |
| Female | 3 (23.08) | 85 (73.28) | 7 (12.28) | 38 (18.18) | 8 (16.00) | 16 (12.03) | |||
| Age (years) | |||||||||
| Mean (SD) | 68.9 (10.78) | 64.2 (10.30) | 0.1516 | 66.8 (12.55) | 64.8 (9.98) | 0.2670 | 66.6 (11.18) | 62.7 (10.30) | 0.0369 |
| Median (IQR) | 69.0 (12.0) | 64.0 (12.5) | 68.0 (18.0) | 65.0 (12.0) | 68.5 (17.0) | 64.0 (13.0) | |||
| Hepatitis B, n (%) | |||||||||
| Yes | 3 (23.08) | 58 (50.00) | 0.0822 | 25 (43.86) | 101 (48.33) | 0.6538 | 29 (58.00) | 77 (57.89) | 1.0000 |
| No | 10 (76.92) | 58 (50.00) | 32 (56.14) | 108 (51.67) | 21 (42.00) | 56 (42.11) | |||
| Hepatitis C, n (%) | |||||||||
| Yes | 5 (38.46) | 19 (16.38) | 0.0660 | 3 (5.26) | 28 (13.40) | 0.1055 | 5 (10.00) | 14 (10.53) | 1.0000 |
| No | 8 (61.54) | 97 (83.62) | 54 (94.74) | 181 (86.60) | 45 (90.00) | 119 (89.47) | |||
| Child-Pugh Score, n (%) | |||||||||
| A | 10 (76.92) | 110 (94.83) | 33 (57.89) | 167 (79.90) | 32 (64.00) | 102 (76.69) | |||
| B | 3 (23.08) | 5 (4.31) | 0.0475 | 24 (42.11) | 39 (18.66) | 0.0012 | 17 (34.00) | 25 (18.80) | 0.0835 |
| C | 0 (0.0) | 1 (0.86) | 0 (0.0) | 3 (1.44) | 1 (2.00) | 6 (4.51) | |||
| ECOG Scores, n (%) | |||||||||
| 0–2 | 13 (100.0) | 116 (100.0) | 53 (92.98) | 200 (95.69) | 0.4855 | 49 (98.00) | 126 (94.74) | 0.4497 | |
| 3–4 | − | − | − | 4 (7.02) | 9 (4.31) | 1 (2.00) | 7 (5.26) | ||
p values are based on Fisher's exact test for categorical variables and 2 sample t test for continuous variables. EOCG, Eastern Cooperative Oncology Group; SD, standard deviation; HCC, hepatocellular carcinoma.