Table 3.
Comparison of median OS and PFS between NCCS compliant groups within each HCC stage
| HCC stage | Status | Median OS (95% CI) | p value | Median PFS (95% CI) | p value |
|---|---|---|---|---|---|
| Early stage HCC | Noncompliant | 23.52 (6.70, ne) | 10.64 (3.35, 51.78) | ||
| Compliant | Median OS not reached | <0.0001 | Median PFS not reached | <0.0001 | |
| Overall | Median OS not reached | 53.39 (28.88, ne) | |||
| Locally advanced-stage HCC | |||||
| No vascular invasion | Noncompliant | 22.21 (7.00, ne) | 23.13 (5.98, ne) | ||
| Compliant | 28.09 (19.65, 40.94) | 0.0216 | 9.43 (6.83, 11.70) | 0.2052 | |
| Overall | 25.66 (19.61, 38.60) | 10.32 (7.96, 11.99) | |||
| Vascular invasion | Noncompliant | 3.29 (2.43, 9.20) | 5.06 (2.27, ne) | ||
| Compliant | 10.25 (6.74, 14.16) | 0.0013 | 6.18 (4.34, 8.48) | 0.4806 | |
| Overall | 8.41 (5.45, 11.83) | 6.05 (4.34, 8.48) | |||
| Metastatic stage HCC | Noncompliant | 6.77 (4.34, 13.50) | 5.36 (3.52, 8.74) | ||
| Compliant | 8.05 (7.10, 10.45) | 0.6300 | 3.98 (3.32, 5.59) | 0.1390 | |
| Overall | 8.02 (6.64, 10.15) | 4.57 (3.48, 5.88) |
ne, not estimable; CI, confidence interval; HCC, hepatocellular carcinoma.