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Percentage of patients who reported symptoms with different endocrine toxicity subtypes
| Endocrine toxicity subtype | Overall number | Symptomatic patients, n (%) |
|---|---|---|
| Primary hypothyroidism | 45 | 25 (55) |
| Thyroiditis | 29 | 17 (58.6) |
| Primary adrenal insufficiency | 1 | 1 (100) |
| Hypophysitis | 9 | 7 (77.7) |
| Secondary hypothyroidism | 11 | 9 (81.8) |
| Secondary adrenal insufficiency | 14 | 13 (92.8) |
| Central hypogonadism | 5 | 5 (100) |
| New onset insulin-dependent DM | 2 | 1 (50) |
Abbreviation: DM, diabetes mellitus
