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. 2021 Jul;27(7):1850–1857. doi: 10.3201/eid2707.203900

Table 4. Clinical characteristics of 17 children who failed 4 rounds of triclabendazole treatment for Fasciola hepatica infection among preschool and school-age children, Cusco, Peru*.

Child Community District Age, y/sex Other parasites HAZ Living under US $3.75/day ERR, %† Total drug dose, mg/kg‡ Additional treatment received
1 Anta Anta 6.8/F Yes −0.6 25 90 1 more round
2 Anta Anta 14.1/M No −2.3 25 40 90 2 more rounds
3 Conchacalla Anta 10.5/M No −1.8 13 67 210 Nitazoxanide
4 Conchacalla Anta 3.2/F No −2.4 36 40 50 2 more rounds
5 Conchacalla Anta 6.0/F No −0.4 36 210 None
6 Inquilpata Anta 8.5/M No −0.9 36 30 50 2 more rounds
7 Inquilpata Anta 9.7/F No −1.2 36 43 50 2 more rounds
8 Inquilpata Anta 3.3/M Yes −1.2 49 +275 210 None
9 Izcuchaca Anta 13.9/F No −0.6 36 +574 150 1 more round
10 Izcuchaca Anta 7.4/M No −0.6 25 63 150 1 more round
11 Mantoclla Anta 7.3/F Yes −2.0 25 10 150 None
12 Mantoclla Anta 9.2/F Yes −1.9 25 31 150 None
13 Caccahuara Ancahuasi 13.1/F No −1.5 25 17 210 Nitazoxanide
14 Caccahuara Ancahuasi 15.5/F No −1.9 13 +50 210 None
15 Caccahuara Ancahuasi 7.8/M No −1.1 25 +100 210 Nitazoxanide
16 Chaquillccasa Ancahuasi 11.5/M Yes −0.9 25 +250 210 None
17 Chaquillccasa Ancahuasi 5.5/F Yes −2.1 49 63 210 1 more round

*ERR, egg reduction rate; HAZ, height-for-age Z score. †Between baseline and after the fourth round of treatment, as estimated by the number of eggs in Kato Katz tests. + signs indicate the percent increase in the egg count. ‡Total cumulative dose received after the fourth round of treatment §Diagnosed only by Lumbreras rapid sedimentation test and a negative Kato Katz test result.