Table. Characteristics of severe acute respiratory syndrome coronavirus 2–positive outpatients attending the Charité–Universitätsmedizin Berlin testing site, by lineages, Germany, January–March 2021*.
| Characteristic | Wild-type lineage | B.1.1.7 variant | OR (95% CI) |
|---|---|---|---|
| Total no. |
125 |
193 |
NA |
| Sex | |||
| M | 69 (55.2) | 94 (49.0) | |
| F |
56 (44.8) |
98 (51.0) |
1.3 (0.8–2.0) |
| Mean age, y (±SD) |
36.6 (±13.8) |
34.8 (±15.9) |
1.8 (−1.5 to 5.1)† |
| Any symptoms | 122 (97.6) | 186 (96.4) | 0.7 (0.2–2.6) |
| Self-reported fever in previous 48 h | 48 (38.4) | 82 (42.5) | 1.2 (0.8–1.9) |
| Median self-reported temperature in case of fever, °C (±SD) | 38.3 (±0.6) | 38.2 (±0.7) | 0.1 (−0.2 to 0.4)§ |
| Shortness of breath | 12 (9.6) | 26 (13.5) | 1.5 (0.7–3.0) |
| Fatigue | 92 (73.6) | 138 (71.5) | 0.9 (0.5–1.5) |
| Chest pain | 3 (2.4) | 2 (1.0) | 0.4 (0.1–2.6) |
| Diarrhea | 19 (15.2) | 24 (12.4) | 0.8 (0.4–1.5) |
| Anosmia or ageusia (loss of smell or taste) | 47 (37.6) | 46 (23.8) | 0.5 (0.3–0.9) |
| Muscle aches | 75 (60.0) | 116 (60.1) | 1.0 (0.6–1.6) |
| Sore throat | 52 (41.6) | 104 (53.9) | 1.6 (1.0–2.6) |
| Cough | 61 (48.8) | 98 (50.8) | 1.1 (0.7–1.7) |
| Headache | 86 (68.8) | 133 (68.9) | 1.0 (0.6–1.6) |
| Chills | 44 (35.2) | 67 (34.7) | 1.0 (0.6–1.6) |
| Rhinorrhea |
76 (60.8) |
102 (52.8) |
0.7 (0.5–1.1) |
| Median duration of symptoms upon test, d (25%–75% quantile) |
3.0 (2.0–4.8) |
3.0 (2.0–4.0) |
0.0 (−1.0 to 0.0)§ |
| Contact with person with confirmed SARS-CoV-2 infection | 60 (48.0) | 97 (50.3) | 1.1 (0.7–1.7) |
| Median time between contact with person with confirmed
SARS-CoV-2 infection and test, d (25%–75% quantile) |
4.0 (1.2–7.0) |
4.0 (1.0–6.0) |
0.0 (−1.5 to 3.0)‡ |
| Travel outside Berlin region in previous 14 d |
12 (9.6) |
36 (18.7) |
2.2 (1.1–4.3) |
| Median Ct value (25%–75% quantile) | 20.2 (17.4–24.1) | 20.1 (17.1–22.8) | 0.1 (−0.9 to 1.6)‡ |
| Symptom duration <7 d, no. patients (median Ct value [25%–75% quantile]) | 113 (19.9 [17.4–23.5]) | 171 (19.5 [16.6–22.6]) | 0.4 (−1.0 to 1.7)‡ |
| Symptom duration >7 d, no. patients (median Ct value [25%–75% quantile]) | 6 (30.1 [26.1–31.3]) | 11 (26.2 [21.4–31.2]) | 3.9 (−5.6 to 10.0)‡ |
*Values are no. (%) except as indicated. Ct, cycle threshold; NA, not applicable; OR, odds ratio; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2. †Difference in means (95% CI). ‡Difference in medians (95% CI). The 95% CI for difference in medians was computed by a percentile bootstrap with 1,000 replications.