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Affinity of IBI323, IBI110 and Bi127 to human PD-L1 and LAG-3 measured by SPR
| Antibody | Antigen | ka (1/Ms) | kd (1/s) | KD (M) |
|---|---|---|---|---|
| IBI323 | hLAG-3 | 2.45 (± 0.01) E05 | 1.69 (± 0.36) E-04 | 6.71 (± 1.34) E-10 |
| IBI110 | 2.59 (± 0.27) E05 | 1.73 (± 0.34)E-04 | 6.77 (± 1.80) E-10 | |
| IBI323 | hPD-L1 | 9.17 (± 0.62) E05 | 1.21 (± 0.14) E-04 | 1.32 (± 0.07) E-11 |
| Bi127 | 2.16 (± 0.06) E06 | 1.80 (± 0.05) E-04 | 8.33 (± 0.01) E-11 |
