Skip to main content
. 2021 Jun 24;12(1):1508–1526. doi: 10.1080/21505594.2021.1932183

Table 5.

Do transmission/virulence traits tend to be oligogenic (i.e. controlled by few genes)? Summary table of the number of loci and genes involved in transmission/virulence or growth life-history traits for various eukaryotic parasite systems (reviewed from the literature)

Parasite system Phenotypes Number of loci involved
(chr. #)
Number of gene(s) involved
(gene name)
Percentage of phenotypic variations explained by the loci References
Toxoplasma gondii Acute virulence 1 (XII) 1 (ROP5) - 97
Acute virulence 3 (VIIa/VIIb/XII) 3 (ROP18/ROP16/ROP5) - 98, 99
Acute virulence 2 (VIIa/Ia) 1 (ROP18) - 100, 101
Growth 4 (VIIa/XI/XII/Ia) - - 102
Migration 1 (VIIa) - - 101
Acute virulence 1 (XII) 1 (ROP5) - 103
Plasmodium yoelii yoelii (rodent malaria parasite] Growth rate 1 (XIII) 1 (pyebl) - 78, 79
Meloidogyne hapla
(plant pathogen nematode)
Egg mass number 2 (VII/XIII) - - 80
Total eggs among F2 lines 2 (IV/VII) - - 80
Schistosoma mansoni Transmission stage production/Virulence 5
(3 major: I/III/V and 2 minor: II/IV)
5 potential best candidate genes (peptidylprolyl isomerase/G-protein coupled receptor kinase/Calmodulin and Nucleoporin_FG2/LYAR cell growth regulating nucleolar protein) 28.56% Present study