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. Author manuscript; available in PMC: 2021 Jun 28.
Published in final edited form as: J Allergy Clin Immunol. 2020 Dec 15;147(3):1031–1040. doi: 10.1016/j.jaci.2020.11.044

Fig 2.

Fig 2.

Manhattan plots from the epigenome-wide association studies performed in three European birth cohorts of childhood allergic disease (discovery). A total of 439,306 CpGs were tested for association. The red dotted horizontal line represents the Bonferroni-corrected threshold (p<1.14 × 10–7) of genome-wide significance. All 21 replicated CpGs are marked as green circles and annotated with CpGs name. (A) Results for the EWAS analysis in children aged 4 years (n=636) from the three European cohorts BAMSE, INMA and PIAMA. (B) Results for the EWAS meta-analysis in children aged 8 years (n=821) from BAMSE and PIAMA.