Table 1. Demographic and clinical data of CF and control subjects.
CF: cystic fibrosis; M: male; F: female; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; NE: neutrophil elastase; CFTR: cystic fibrosis transmembrane conductance regulator; MRSA: methicillin-resistant staphylococcus aureus
| CF (N=21) | Control (N=22) | P-value | |
| Gender (M/F), N | 13/8 | 10/12 | 0.281 |
| Age in years: mean (±SD) | 24.29 ± 5.28 | 31.59 ± 10.37 | 0.003 |
| CFTR genotype, N (%) homozygous CFTRI1234V mutation homozygous F508del/ F508del | 20/21 (95.24%) 1/21 (4.76%) | ||
| BMI (kg/m2): mean(±SD) | 24.09±5.43 | 26.59 ± 3.93 | 0.092 |
| Plasma NE: median (range) (ng/ml) | 17.67 (0.79-340.22) | 10.65 (0.91-29.57) | 0.067 |
| Sputum NE: median (range) (ng/ml) | 3.78 (0.39-32.44) | - | - |
| Pseudomonas aeruginosa chronic colonized in lower respiratory secretion, N (%) | 16/21 (76.2%) | - | - |
| MRSA, N (%) | 1/21 (4.8%) | - | - |
| % Predicted FEV1: mean(±SD) | 66.62 ± 20.04 | - | - |
| % Predicted FVC: mean(±SD) | 73.43 ± 16.21 | - | - |
| % Predicted FEV1/ FVC: mean(±SD) | 77.67 ± 11.749 | - | - |