Table 2.

Models predicting coma, accounting for SIRS score of ≥ 2 and number of days with a SIRS score ≥ 2

	Coma, n (%)	SIRS ≥ 2, HR (95% CI)	Days with SIRS ≥ 2, HR (95% CI)
All patients	1054 (32.9)	5.92 (5.03–6.97)	5.05 (4.27–5.98)
Neuromuscular blocking agents with sedatives or opiatesa	197 (97.5)	1.33 (0.33–5.37)	1.61 (0.39–6.61)
Sedatives or opiates, without neuromuscular blocking agentsa	720 (75.6)	1.90 (1.58–2.29)	1.94 (1.59–2.36)
No neuromuscular blocking agents, sedatives, or opiatesa	137 (6.7)	5.08 (3.47–7.34)	4.70 (3.09–7.15)

Data reported as N (%)

CI confidence interval, HR hazard ratio, SIRS systemic inflammatory response syndrome

^aMedications listed here for stratification of the group include only those give prior to the onset of coma