Table 1.
Overview of AMPs from different sources in nature and the current status of research.
AMPs from Microorganism | |||||
---|---|---|---|---|---|
Class | Source | Peptide Name | Biological activity | Studies | Reference |
Bacteriocin | Bacteria Bacillus spp. |
Mersacidin | Antibacterial | In vivo |
Jenssen et al., 2006
Kruszewska et al., 2004 |
Bacteriocin | Bacteria Lactobacillus gasseri |
Lactocillin | Antibacterial | In vitro |
Magana et al., 2020
Donia et al., 2014 |
Bacteriocin | Bacteria Lactococcus lactis |
Nisin | Antibacterial | Clinical practice | Dijksteel et al., 2021 |
Bacteriocin | Bacteria Bacillus subtilis |
Ericin | Antibacterial | In vitro | Sharma et al., 2018 |
Defensin | Fungi Penicillium chrysogenum |
PAF | Antifungal | In vivo |
Kaiserer et al., 2003
Barna et al., 2008 Marx, 2004 Palicz et al., 2016 |
Defensin | Fungi Aspergillus giganteus |
AFP | Antifungal | In vitro |
Hegedüs and Marx, 2013
Krishnamurthy et al., 2020 |
AMPs from Plants | |||||
Defensin | Phaseolus vulgaris | PvD1 | Antifungal | In vitro |
Mello et al., 2011
do Nascimento et al., 2015 |
Defensin | Persea americana | PaDef | Antibacterial | In vitro | Guzmán-Rodríguez et al., 2013 |
Thionin | Triticum aestivum | α1-purothionin | Antibacterial | In vitro |
de Caleya et al., 1972
Oard et al., 2012 |
Snakin | Ziziphus jujuba | Snakin-Z | Antifungal | In vitro |
Daneshmand et al., 2013
Meneguetti et al., 2017 |
AMPs from Insects | |||||
Cecropin | Hyalophora cecropia | CecA | Antibacterial | In vitro |
Wu Q. et al., 2018
Wang et al., 2017 |
Cecropin | Spodoptera litura | Spodopsin Ia | Antibacterial | Discovery | Choi et al., 1997 |
Defensin | Drosophila melanogaster | Drosomycin | Antifungal | In vitro |
Landon et al., 1997
Fehlbaum et al., 1994 |
Proline-rich AMPs | Apis mellifera | Abaecin | Antibacterial | In vitro |
Casteels et al., 1990
Luiz et al., 2017 |
Attacin | Hyphantria cunea | Attacin-B | Antibacterial | In vitro | Kwon et al., 2008 |
Glycine-rich AMPs | Drosophila melanogaster | Diptericin | Antibacterial | In vitro |
Verma and Tapadia, 2012
Wicker et al., 1990 |
AMPs from Animals | |||||
Cathelicidin | Bovine | BMAP-28 | Antibacterial | In vivo |
Risso et al., 2002
Benincasa et al., 2003 |
Brevinin | Rana boylii | Brevinin-1BYa | Antifungal | In vivo |
Conlon et al., 2003
Liu et al., 2017 |
Cathelicidin | Pig | Protegrin-1 | Antibacterial | In vitro |
Soundrarajan et al., 2019
Huynh et al., 2018 |
AMPs from Humans | |||||
Cathelicidin | Human granulocytes | hCAP18/LL-37 | Antibacterial | Clinical trial | Leszczynska et al., 2013 |
Defensin | Human monocytes | hBD1 hBD2 hBD3 |
Antibacterial | In vivo |
Levón et al., 2015
Maiti et al., 2014 |
Histatin | Human saliva | Histatin-1 | Antibacterial Antifungal |
Clinical practice | Khurshid et al., 2017 |