Table 2.

Renal gene expression at PD70

	Male			Female			DietP	SexP	Diet × SexP
Gene	0.04%(n = 5)	0.15%(n = 5)	0.30%(n = 5)	0.04%(n = 4)	0.15%(n = 5)	0.30%(n = 5)
Renin(Ren)	1.34(1.18–1.52)	1.00(0.87–1.15)	1.05(0.89–1.24)	1.95(1.56–2.44)	2.18(1.89–2.51)	1.64(1.53–1.75)	0.37	<0.01	0.34
AT1A(Agtr1a)	1.14 c(0.93–1.41)	1.00 c(0.92–1.09)	5.15a,b(3.15–8.43)	0.85b(0.73–1.00)	2.62a,c(2.10–3.25)	2.39a(2.16–2.64)	<0.01	0.91	<0.01
NCC(Slc12a3)	1.20c(1.06–1.35)	1.00c(0.92–1.09)	0.13a,b(0.10–0.16)	1.54c(1.18–2.01)	0.73c(0.47–1.15)	0.19a,b(0.16–0.23)	<0.01	0.65	0.33
NHE3(Slc9a3)	1.13c(1.03–1.25)	1.00c(0.94–1.07)	1.64a,b(1.46–1.83)	0.98c(0.86–1.12)	1.22(1.12–1.33)	1.37a(1.26–1.49)	<0.01	0.62	0.11
Na-K-ATPase(Atp1a1)	1.25(1.14–1.38)	1.00(0.91–1.10)	1.56(1.30–1.86)	1.40(1.09–1.79)	1.49(1.37–1.62)	1.55(1.34–1.80)	0.22	0.22	0.33
NKCC2a(Slc12a1)	1.33(1.25–1.41)	1.00 c(0.95–1.06)	1.65b(1.40–1.93)	1.74(1.45–2.09)	1.97(1.70–2.27)	2.33(2.10–2.59)	0.03	<0.01	0.14
ENaCα(Scnn1a)	1.20(1.07–1.35)	1.00(0.91–1.10)	1.49(1.29–1.72)	1.79(1.69–1.89)	2.26(2.02–2.53)	2.32(2.08–2.58)	0.05	<0.01	0.08

Data presented as means (±1 SE) fold of 0.15% Na diet male group.

^aP < 0.05 vs. 0.04% within sex, ^bP < 0.05 vs. 0.15% group within sex, and ^cP < 0.05 vs. 0.30% group within sex by Tukey’s multiple comparison procedure.