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. 2021 Jun 25;100(25):e26214. doi: 10.1097/MD.0000000000026214

Table 1.

Association between CD45RO+ratio and clinicopathological characteristics.

CD45RO+ratio
<1.07 ≥1.07
Variables n=95 n=90 P value
Sex
 Male 57 (60.0%) 53 (58.9%) .878
 Female 38 (40.0%) 37 (41.1%)
Age (yrs)
 <60 65 (68.4%) 60 (66.7%) .799
 ≥60 30 (31.6%) 30 (33.3%)
Distance from anal verge (cm)
 <5 37 (38.9%) 35 (38.9%) .993
 ≥5 58 (61.1%) 55 (61.1%)
pre-CRT CEA level (ng/mL)
 <5 47 (49.5%) 47 (52.2%) .709
 ≥5 48 (50.5%) 43 (47.8%)
Tumour differentiation
 G1-2 58 (61.1%) 68 (75.6%) .034
 G3-4 37 (38.9%) 22 (24.4%)
Clinical stage
 II 29 (30.5%) 26 (28.9%) .808
 III 66 (69.5%) 64 (71.1%)
Surgery
 Anterior resection 61 (64.2%) 65 (72.2%) .243
 Nonanterior resection 34 (35.8%) 25 (27.8%)
TRG
 TRG0-1 21 (22.1%) 32 (35.6%) .043
 TRG2-3 74 (77.9%) 58 (64.4%)
ypT
 T0 6 (6.3%) 3 (3.3%) .001
 T1–2 21 (22.1%) 42 (46.7%)
 T3–4 68 (71.6%) 45 (50.0%)
ypN
 N0 50 (52.6%) 60 (66.7%) .052
 N1–2 45 (47.4%) 30 (33.3%)
ypTNM stage
 ypCR 9 (9.5%) 11 (12.2%) .012
 I 16 (16.8%) 33 (36.7%)
 II 27 (28.4%) 19 (21.1%)
 III 43 (45.3%) 27 (30.0%)
LVI
 Negative 82 (86.3%) 80 (88.9%) .596
 Positive 13 (13.7%) 10 (11.1%)

CEA= carcinoembryonic antigen, CRT = chemoradiotherapy, LVI = lymphovascular invasion.

CD45RO+ratio-high was associated with lower tumor regression grade grading (P = .031), T stage (P = .001), and TNM stage (P = .012).