Table 3.

Univariate and multivariate survival analysis of male esophageal cancer patients with bone alone, liver alone, lung alone, and simultaneous liver and lung metastasis.

	Univariate analysis	Multivariate analysis
Characteristics	P	Hazard ratio	95%CI	P value
Age at diagnosis (year)	<.001			.011
≤60		Reference
>60		1.062	1.014–1.113	.011
Race	<.001			<.001
Black		Reference
White		0.921	0.852–0.995	.038
Others		0.867	0.775–0.971	.014
Unknown		0.401	0.247–0.652	<.001
Primary site	.010			<.001
Upper1/3		Reference
Middle1/3		1.178	1.062–1.306	.002
Lower1/3		1.217	1.101–1.346	<.001
Overlapping lesion		1.460	1.280–1.665	<.001
Unknown		1.272	1.129–1.432	<.001
Histopathology type	<.001			<.001
Squamous cell carcinoma		Reference
Adenocarcinoma		0.844	0.794–0.898	<.001
Others		0.964	0.882–1.053	.414
Pathology grade	<.001			<.001
I well-differentiated		Reference
II moderately		1.430	1.275–1.605	<.001
III poorly differentiated		1.872	1.670–2.098	<.001
IV undifferentiated		1.932	1.564–2.386	<.001
Unknown		1.295	1.149–1.461	<.001
Surgery	<.001			<.001
No		Reference
Yes		0.277	0.261–0.295	<.001
Unknown		0.652	0.543–0.782	<.001
Radiotherapy	<.001			.526
No		Reference
Yes		1.017	0.966–1.070	.526
Chemotherapy	<.001			<.001
No		Reference
Yes		0.534	0.507–0.562	<.001
Marital status	<.001			<.001
Unmarried		Reference
Married		0.846	0.809–0.885	<.001
Unknown		0.802	0.725–0.886	<.001
Residence type	.882	NA
Rural
Urban
Unknown
Insurance situation	<.001			<.001
Insurance		Reference
No insurance		1.262	1.132–1.406	<.001
Unknown		0.850	0.730–0.989	.035
Metastasis	<.001			<.001
None		Reference
Bone only		2.105	1.910–2.320	<.001
Liver only		1.836	1.712–1.968	<.001
Lung only		1.609	1.458–1.776	<.001
Liver and lung		2.372	2.146–2.623	<.001

CI = confidence intervals.