Table 3.

Receiver-operating characteristic analysis of Hexokinase 2 (HK2) in peripheral blood mononuclear cells from patients with Rheumatoid arthritis (RA) and Osteoarthritis (OA).

Group	AUC (95%CI)	P-value	Cut off value	Sensitivity (95%CI)	Specificity (95%CI)
RA vs HCs	0.808 (0.725–0.891)	<.001	0.0113	80.00% (68.23%–89.90%)	72.50% (56.11%-85.40%)
OA vs HCs	0.640 (0.514–0.766)	.04	0.0097	48.57% (31.38%–66.01%)	65.00% (48.32%-79.37%)
RA vs OA	0.655 (0.536–0.773)	.01	0.0193	55.38% (42.53%–67.73%)	62.86% (44.92%- 78.53%)

RA = Rheumatoid arthritis; OA = Osteoarthritis; HCs = heathy controls; HK2 = Hexokinase 2; AUC = Area under the curve; CI = confidence interval.