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. 2021 Jun 14;12:679580. doi: 10.3389/fphar.2021.679580

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Copyright © 2021 Yang, Chen, Huang, Fan, Yang, Wang, Li, Niu and Liao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The GFP-plasmid transfected cells were cultured with CMCTS (Control), LPS/CMCTS (LPS), LPS/CMCTS-Tk, and LPS/Cur@CMCTS-Tk hydrogel for 72 h. (B) Images for cell wound scratch assay of L929 cells at 72 h. (C) Cytotoxicity of Cur@CMCTS-Tk hydrogel to fibroblast cells by MTT assay at 24 and 72 h. (D) Quantitative analysis of the scratch area. The data were represented as mean ± SD (n = 6), **p < 0.01 vs. control; ^## p < 0.01 vs. LPS/CMCTS (LPS) group.