Figure 2.

Differences at global scale

(A) UMAP of taxonomic profiles based on Jaccard distance between samples. Colored by the region of origin for each sample. Axes are arbitrary and without meaningful scale. The color key is shared with (B).

(B) Association of the first 25 principal components of sample taxonomy with climate, continent, and surface material.

(C) Distribution of ma1jo0r phyla, sorted by hierarchical clustering of all samples and grouped by continent.

(D) Distribution of high-level groups of functional pathways, using the same order as taxa (C).

(E) Distribution of AMR genes by drug class (as defined in MegaRes), using the same order as taxa (C). Note that MLS is macrolide-lincosamide-streptogramin.

See also Figure S3.