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. 2021 Jun 24;14:2785–2797. doi: 10.2147/IJGM.S312521

Table 3.

Clinical Biochemical Tests of COVID-19 Patients

Indicators Total Within the First Week p value Total Within the Second Week p value Total Within the Third or Fourth Week p value
n=79 Normal Albumin (n=77) Hypoalbuminemia (n=2) n=79 Normal Albumin (n=67) Hypoalbuminemia (n=12) n=79 Normal Albumin (n=72) Hypoalbuminemia (n=7)
Prealbumin (g/L) 209.00(161.00–280.0) 212.00(162.00–283.50) 108.50(105.75–111.25) 0.009 225.50(176.00–274.75) 247.00(201.75–282.50) 171.00(157.25–183.50) 0.000 311.50(238.00–351.00) 323.00(272.50–357.00) 197.00(181.00–216.00) 0.000
Alanine aminotransferase (ALT) 19.00(13.00–37.50) 19.00(13.00–36.00) 28.10(20.05–36.15) 0.962 21.00(16.00–33.00) 20.50(15.25–30.75) 35.00(18.50–61.50) 0.119 24.00(14.25–30.00) 23.50(14.75–29.25) 37.00(15.00–83.75) 0.303
Aspartate aminotransferase (AST) 23.00(18.00–32.50) 23.00(18.00–32.00) 39.75(30.38–49.13) 0.374 20.00(17.00–28.00) 16.00(16.00–25.25) 39.00(21.00–42.00) 0.171 19.00(15.00–23.00) 19.00(15.00–22.00) 25.50(21.25–38.75) 0.062
PCT 0.02(0.02–0.04) 0.02(0.02–0.04) 0.14(0.14–0.15) 0.003 0.02(0.02–0.05) 0.02(0.02–0.02) 0.05(0.02–0.09) 0.067 0.04(0.02–0.05) 0.03(0.02–0.05) 0.04(0.03–0.04) 0.661
Globulin 25.80(23.30–29.90) 25.90(23.50–30.00) 22.40(22.30–22.50) 0.146 25.30(22.90–29.00) 25.20(22.50–28.40) 26.95(24.20–33.58) 0.085 25.80(22.80–28.50) 25.70(22.75–28.50) 28.55(25.43–32.43) 0.210
Total bilirubin 14.60(10.60–19.90) 14.60(10.70–19.60) 22.50(14.05–30.95) 0.987 15.40(10.80–21.00) 14.20(10.55–19.15) 21.35(13.85–27.43) 0.041 12.15(9.38–12.15) 12.15(9.53–14.93) 12.70(8.45–15.68) 0.874
Urea nitrogen 3.92(3.11–4.69) 3.92(3.12–4.65) 4.04(3.52–4.55) 0.818 3.68(2.79–4.41) 3.67(2.79–4.34) 4.30(2.62–5.34) 0.352 3.75(3.07–4.23) 3.75(3.10–4.22) 3.07(3.05–4.06) 0.916
Uric acid 287.50(237.75–334.75) 288.00(237.50–335.50) 259.00(256.00–262.00) 0.711 321.00(263.00–359.00) 321.00(264.00–358) 293.00(260.00–326.00) 0.011 317.50(246.25–413.25) 333.00(252.00–414.75) 198.50(120.75–292.75) 0.011
Creatinine 67.90(54.63–77.28) 67.90(54.38–77.75) 67.30(63.75–71.25) 0.865 64.60(56.20–75.10) 64.70(56.15–75.88) 62.60(56.90–74.10) 0.958 64.80(54.80–80.30) 64.5(54.75–80.65) 69.65(64.38–73.43) 0.763
β2-microglobulin 2.35(1.58–2.93) 2.35(1.58–2.90) 3.10(2.72–3.49) 0.107 1.82(1.58–2.31) 1.82(1.57–2.31) 2.53(2.40–2.66) 0.423 1.72(1.39–2.13) 1.71(1.39–2.04) 2.31(1.92–2.66) 0.203
CystatinC 0.92(0.84–1.10) 0.92(0.84–1.10) 0.65(0.37–0.93) 0.267 0.91(0.85–1.07) 0.90(0.84–1.06) 1.06(1.00–1.13) 0.017 1.00(0.84–1.10) 0.98(0.84–1.10) 1.14(0.99–1.19) 0.311