Table 1.
Formulation code | Ingredients (mg/tablet) | ||||
---|---|---|---|---|---|
Disintegrant | Disintegrant | Binder | Diluent | Lubricant and glidant | |
Pectin | Starch | Tragacanth | Lactose | Talc | |
F1–F5 | 31.0 | — | 7.5 | 89.0 | 2.5 |
F6 | — | 31.0 | 7.5 | 89.0 | 2.5 |
F7–F11 | 46.5 | - | 7.5 | 73.5 | 2.5 |
F12 | — | 46.5 | 7.5 | 73.5 | 2.5 |
F13–F17 | 62.0 | — | 6.5 | 58.0 | 3.5 |
F18 | — | 62.0 | 6.5 | 58.0 | 3.5 |
Paracetamol (500 mg) was used as the active pharmaceutical ingredient (API) in each formulation. Batches F1–F5 contained pectin from the various genotypes in the order PC1–PC5. Batches F7–F11 contained pectin from the various genotypes in the order PC1–PC5. Batches F13–F17 contained pectin from the various genotypes in the order PC1–PC5.