Skip to main content
. 2021 Jun 19;2021:2902335. doi: 10.1155/2021/2902335

Table 4.

Physical and mechanical properties of paracetamol batches produced using different concentrations of the okra pectin as disintegrant.

Formulation code Average weight (g) n = 20 Tablet thickness (mm) n = 20 Tablet diameter (mm) n = 20 Hardness (kg/F) n = 6 Friability (%) Disintegration time (DT) (min) n = 2 Drug content (%) n = 3
F1 0.630 ± 0.003 3.70 ± 0.093 13.07 ± 0.235 5.60 ± 0.539 0.330 11.40 ± 0.265 99.61 ± 0.03
F2 0.630 ± 0.001 3.98 ± 0.073 13.04 ± 0.009 4.88 ± 1.308 0.139 14.20 ± 0.398 99.61 ± 0.07
F3 0.620 ± 0.001 3.78 ± 0.145 13.03 ± 0.015 7.38 ± 2.46 0.005 10.40 ± 0.447 100.12 ± 0.01
F4 0.620 ± 0.001 3.61 ± 0.092 13.06 ± 0.025 5.92 ± 1.264 0.002 8.90 ± 0.566 99.92 ± 0.10
F5 0.621 ± 0.002 3.96 ± 0.104 13.08 ± 0.051 6.44 ± 1.405 0.011 19.20 ± 0.100 99.82 ± 0.03
F6 0.620 ± 0.001 3.76 ± 0.099 13.07 ± 0.025 4.02 ± 0.861 0.005 9.87 ± 0.640 99.75 ± 0.08
F7 0.630 ± 0.002 3.74 ± 0.043 13.03 ± 0.011 6.4 ± 0.57 0.000 10.60 ± 0.148 99.82 ± 0.10
F8 0.632 ± 0.002 3.87 ± 0.132 13.02 ± 0.085 4.92 ± 0.719 0.002 9.09 ± 0.122 99.30 ± 0.04
F9 0.629 ± 0.002 3.88 ± 0.112 13.04 ± 0.015 8.14 ± 2.519 0.002 11.08 ± 0.898 97.46 ± 0.01
F10 0.631 ± 0.002 3.95 ± 0.109 13.05 ± 0.017 8.60 ± 2.742 0.005 12.22 ± 0.867 98.26 ± 0.03
F11 0.631 ± 0.005 3.94 ± 0.134 13.04 ± 0.017 6.74 ± 2.703 0.009 19.39 ± 0.145 99.59 ± 0.11
F12 0.621 ± 0.002 3.78 ± 0.087 13.05 ± 0.401 4.62 ± 0.563 0.174 9.39 ± 1.07 99.56 ± 0.03
F13 0.629 ± 0.001 3.68 ± 0.094 13.05 ± 0.012 6.56 ± 0.467 0.265 10.98 ± 0.989 99.71 ± 0.01
F14 0.621 ± 0.002 3.87 ± 0.068 13.09 ± 0.025 6.20 ± 0.663 0.742 8.78 ± 1.023 99.00 ± 0.10
F15 0.630 ± 0.003 3.67 ± 0.096 13.07 ± 0.018 7.34 ± 2.062 0.017 10.53 ± 0.895 97.63 ± 0.20
F16 0.630 ± 0.002 3.72 ± 0.203 13.04 ± 0.008 3.74 ± 1.152 0.002 10.49 ± 1.023 99.29 ± 0.03
F17 0.631 ± 0.003 3.88 ± 0.138 13.08 ± 0.013 7.10 ± 0.866 0.256 25.04 ± 0.987 101.36 ± 0.02
F18 0.639 ± 0.002 3.82 ± 0.067 13.08 ± 0.045 7.42 ± 0.287 0.196 9.05 ± 0.989 99.00 ± 0.11