Table 4.
Formulation code | Average weight (g) n = 20 | Tablet thickness (mm) n = 20 | Tablet diameter (mm) n = 20 | Hardness (kg/F) n = 6 | Friability (%) | Disintegration time (DT) (min) n = 2 | Drug content (%) n = 3 |
---|---|---|---|---|---|---|---|
F1 | 0.630 ± 0.003 | 3.70 ± 0.093 | 13.07 ± 0.235 | 5.60 ± 0.539 | 0.330 | 11.40 ± 0.265 | 99.61 ± 0.03 |
F2 | 0.630 ± 0.001 | 3.98 ± 0.073 | 13.04 ± 0.009 | 4.88 ± 1.308 | 0.139 | 14.20 ± 0.398 | 99.61 ± 0.07 |
F3 | 0.620 ± 0.001 | 3.78 ± 0.145 | 13.03 ± 0.015 | 7.38 ± 2.46 | 0.005 | 10.40 ± 0.447 | 100.12 ± 0.01 |
F4 | 0.620 ± 0.001 | 3.61 ± 0.092 | 13.06 ± 0.025 | 5.92 ± 1.264 | 0.002 | 8.90 ± 0.566 | 99.92 ± 0.10 |
F5 | 0.621 ± 0.002 | 3.96 ± 0.104 | 13.08 ± 0.051 | 6.44 ± 1.405 | 0.011 | 19.20 ± 0.100 | 99.82 ± 0.03 |
F6 | 0.620 ± 0.001 | 3.76 ± 0.099 | 13.07 ± 0.025 | 4.02 ± 0.861 | 0.005 | 9.87 ± 0.640 | 99.75 ± 0.08 |
F7 | 0.630 ± 0.002 | 3.74 ± 0.043 | 13.03 ± 0.011 | 6.4 ± 0.57 | 0.000 | 10.60 ± 0.148 | 99.82 ± 0.10 |
F8 | 0.632 ± 0.002 | 3.87 ± 0.132 | 13.02 ± 0.085 | 4.92 ± 0.719 | 0.002 | 9.09 ± 0.122 | 99.30 ± 0.04 |
F9 | 0.629 ± 0.002 | 3.88 ± 0.112 | 13.04 ± 0.015 | 8.14 ± 2.519 | 0.002 | 11.08 ± 0.898 | 97.46 ± 0.01 |
F10 | 0.631 ± 0.002 | 3.95 ± 0.109 | 13.05 ± 0.017 | 8.60 ± 2.742 | 0.005 | 12.22 ± 0.867 | 98.26 ± 0.03 |
F11 | 0.631 ± 0.005 | 3.94 ± 0.134 | 13.04 ± 0.017 | 6.74 ± 2.703 | 0.009 | 19.39 ± 0.145 | 99.59 ± 0.11 |
F12 | 0.621 ± 0.002 | 3.78 ± 0.087 | 13.05 ± 0.401 | 4.62 ± 0.563 | 0.174 | 9.39 ± 1.07 | 99.56 ± 0.03 |
F13 | 0.629 ± 0.001 | 3.68 ± 0.094 | 13.05 ± 0.012 | 6.56 ± 0.467 | 0.265 | 10.98 ± 0.989 | 99.71 ± 0.01 |
F14 | 0.621 ± 0.002 | 3.87 ± 0.068 | 13.09 ± 0.025 | 6.20 ± 0.663 | 0.742 | 8.78 ± 1.023 | 99.00 ± 0.10 |
F15 | 0.630 ± 0.003 | 3.67 ± 0.096 | 13.07 ± 0.018 | 7.34 ± 2.062 | 0.017 | 10.53 ± 0.895 | 97.63 ± 0.20 |
F16 | 0.630 ± 0.002 | 3.72 ± 0.203 | 13.04 ± 0.008 | 3.74 ± 1.152 | 0.002 | 10.49 ± 1.023 | 99.29 ± 0.03 |
F17 | 0.631 ± 0.003 | 3.88 ± 0.138 | 13.08 ± 0.013 | 7.10 ± 0.866 | 0.256 | 25.04 ± 0.987 | 101.36 ± 0.02 |
F18 | 0.639 ± 0.002 | 3.82 ± 0.067 | 13.08 ± 0.045 | 7.42 ± 0.287 | 0.196 | 9.05 ± 0.989 | 99.00 ± 0.11 |