Figure 1.
Schematic overview of the S proteins from SARS-CoV-2 variants B.1.617 and B.1.351
The location of the mutations in the context of the B.1.617 or B.1.351 S protein domain organization is shown in the upper panel. RBD, receptor binding domain; TD, transmembrane domain. The location of the mutations in the context of the trimeric S protein is shown in the lower panels. Color code: light blue, S1 subunit with RBD in dark blue; gray, S2 subunit; orange, S1/S2 and S2′ cleavage sites; red, mutated amino acid residues.