Table 5.

Most important AS concepts according to clinical experts and caregivers

Concept	Symptoms reported as most challenging, by clinicians (n = 3)	Symptoms most frequently reported, by caregivers (n ≥ 20)	Symptoms reported as most challenging, by caregivers (n = 30)	Most important focus for new treatment, by caregivers (n = 30)	Most important focus for new treatment, by clinicians (n = 3)
Communication	✓	✓	✓	✓	✓
Seizures	✓	✓	✓	✓	–
Maladaptive behaviors	✓	✓	✓	–	✓
Cognition	✓	✓	–	✓	–
Motor	✓	✓	✓	✓	–
Sleep	✓	✓	✓	✓	✓
Self-care	✓	✓	✓	–	–