Table 5.
Cross-week changes of CC16 in blood serum and cellular and humoral parameters of nasal lavage fluid, comparison of study groups (median; min–max)
| Time | Reference (n = 12/22a) | Moderately exposed (n = 8/17a) | Highly exposed (n = 14/22) | |
|---|---|---|---|---|
| CC16 (ng/mL) | Monday | 8.6 (4.3–25.0) | 8.0 (4.1–12.4) | 7.8 (3.8–13.0) |
| Thursday | 7.8 (4.7–18.2) | 6.7 (3.6–12.3) | 5.8 (4.0–11.0) | |
| Total cell count (× 104) | Monday | 4.6; 4.4–23.2 | 4.6; 4.4–67.2 | 6.7; 4.4–32.5 |
| Thursday | 4.6; 4.4–22.5 | 8.9; 4.4–27.0 | 8.9; 4.4–45.6 | |
| Neutrophils (× 103) | Monday | 25.3; 1–86 | 30.0; 1–93 | 23.3; 0.5–96 |
| Thursday | 31.0; 3.5–90 | 36.0; 1–77 | 21.3; 1.5–77.5 | |
| Epithelial cells (× 103) | Monday | 80.3; 14–100 | 70.5; 6.5–100 | 83.5; 4–100 |
| Thursday | 78.3; 10–100 | 64.5; 23.0–100 | 83; 22.5–100 | |
| Total protein (µg/mL) | Monday | 53; 10–124 | 34; 10–152 | 26; 10–338 |
| Thursday | 38.5; 10–76 | 43; 10–154 | 32.5; 10–184 | |
| IL-8 (pg/mL) | Monday | 352; 3–3931 | 217; 3–1227 | 168; 17–2034 |
| Thursday | 209; 3–1601 | 188; 3–1329 | 235; 16–2451 | |
| MMP-9 (ng/mL) | Monday | 38; 0.8–151 | 19; 0.03–165 | 22; 0.03–603 |
| Thursday | 23; 0.5–197 | 43; 0.03–452 | 55; 0.03–613 | |
| TIMP-1 (ng/mL) | Monday | 11.0; 0.3–38.6 | 6.0; 0.03–33.7 | 5.5; 0.03–29.7 |
| Thursday | 9.7; 0.6–27.3 | 7.2; 0.03–36.8 | 6.5; 0.03–43.8 | |
| LTB4 (pg/mL) | Monday | 32.9; 18–407 | 27.8; 16–205 | 33.0; 14–689 |
| Thursday | 39.0; 15–200 | 28.3; 12–237 | 40.9; 12–306 | |
| 8-Iso-prostane (pg/mL) | Monday | 140.8; 96.7–447.7 | 135.0; 44.5–290.1 | 143.9; 63.4–363.9 |
| Thursday | 125.9; 71.7–290.4 | 142.3; 59.8–317.4 | 153.0; 79.3–415.5 | |
| Substance P (pg/mL) | Monday | 30.0; 9.8–86.2 | 28.1; 12.0–42.6 | 20.2; 13.3–40.0 |
| Thursday | 30.5; 14.3–69.1 | 23.5; 14.4–50.2 | 24.0; 11.4–56.7 |
aMissing values were below limit of quantification (LOQ)