Table 6:
Staphylococcus aureus (SA) vs Streptococcus pyogenes (GAS)
| Characteristic | SA (N=228) | GAS(N=21) | ||
|---|---|---|---|---|
| N | Median (IQR) | N | Median (IQR) | |
| Age at admission (yrs) | 228 | 8.80 (3.60, 11.60) | 21 | 6.10 (2.90, 7.80) |
| Female, n (%) | 228 | 76 (33%) | 21 | 10 (48%) |
| Duration of hospitalization (days) | 228 | 7.00 (5.00, 10.50) | 21 | 4.00 (3.00, 8.00) |
| Total (IV + PO) duration of antibiotic treatment (days) | 227 | 42.00 (31.00, 52.00) | 21 | 36.00 (29.00, 47.00) |
| Peak CRP (mg/L) during hospitalization | 228 | 158.00 (76.00, 245.00) | 21 | 129.00 (62.00, 184.00) |
| Peak WBC count (*103) during hospitalization | 222 | 13.00 (10.00, 17.00) | 21 | 14.00 (12.00, 22.00) |
| Peak ESR (mm/hr) during hospitalization | 202 | 65.50 (38.00, 88.00) | 19 | 57.00 (44.00, 80.00) |
| Infection Type, n (%) | ||||
| Both | 228 | 76 (33%) | 21 | 5 (24%) |
| Osteomyelitis | 228 | 127 (56%) | 21 | 7 (33%) |
| Septic Arthritis | 228 | 25 (11%) | 21 | 9 (43%) |
| Bacteremia, n (%) | 214 | 156 (73%) | 18 | 7 (39%) |
| Persistent bacteremia (>72 h), n (%) | 214 | 52 (24%) | 18 | 0 (0%) |
| Surgery performed, n (%) | 228 | 187 (82%) | 21 | 18 (86%) |
| ICU required, n (%) | 228 | 41 (18%) | 21 | 4 (19%) |
| PO therapy at discharge, n (%) | 228 | 135 (59%) | 21 | 15 (71%) |
| Function at end of therapy, n (%) | ||||
| Cast | 185 | 4 (2%) | 19 | 0 (0%) |
| Full ROM | 185 | 151 (82%) | 18 | 16 (89%) |
| Pain at end of therapy, n (%) | ||||
| None | 185 | 135 (73%) | 19 | 17 (89%) |
| Mild | 185 | 43 (23%) | 19 | 2 (11%) |
| Moderate | 185 | 7 (4%) | 19 | 0 (0%) |
| Pathologic fracture, n (%) | 225 | 12 (5%) | 21 | 0 (0%) |
| Concern for recurrence of infection/treatment failure, n (%) | 225 | 26 (12%) | 21 | 1 (5%) |