Table 2:
HLA allelic frequencies for the full GAD cohort, GAD by race and GAD by case/control status for alleles with an allelic frequency of ≥ 0.05. See supplemental Table 1 for all alleles.
| Full GAD n=852 | European Ancestry n=503 | African Ancestry n=318 | All Controls n=388 | All Cases n=464 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Allele | n | AF (95% CI) | n | AF (95% CI) | n | AF (95% CI) | n | AF (95% CI) | n | AF (95% CI) |
| A*01:01 | 182 | 0.11 (0.09,0.12) | 158 | 0.16 (0.14,0.18) | 20 | 0.03(0.02,0.05) | 115 | 0.15 (0.12,0.18) | 67 | 0.07 (0.06,0.09) |
| A*02:01 | 305 | 0.18 (0.16,0.20) | 241 | 0.24 (0.21,0.27) | 59 | 0.09(0.07,0.12) | 162 | 0.21 (0.18,0.24) | 143 | 0.15 (0.13,0.18) |
| A*03:01 | 215 | 0.13 (0.11,0.14) | 150 | 0.15 (0.13,0.17) | 63 | 0.10(0.08,0.12) | 102 | 0.13 (0.11,0.16) | 113 | 0.12 (0.10,0.14) |
| A*24:02 | 106 | 0.06 (0.05,0.07) | 81 | 0.08 (0.06,0.10) | 15 | 0.02(0.01,0.04) | 55 | 0.07 (0.05,0.09) | 50 | 0.05 (0.04,0.07) |
| B*07:02 | 162 | 0.09 (0.08,0.11) | 103 | 0.10 (0.08,0.12) | 52 | 0.08(0.06,0.11) | 94 | 0.12 (0.10,0.15) | 68 | 0.07 (0.06,0.09) |
| B*08:01 | 120 | 0.07 (0.06,0.08) | 101 | 0.10 (0.08,0.12) | 17 | 0.03(0.02,0.04) | 60 | 0.08 (0.06,0.10) | 60 | 0.06 (0.05,0.08) |
| B*35:01 | 95 | 0.06 (0.05,0.07) | 53 | 0.05 (0.04,0.07) | 41 | 0.06(0.05,0.09) | 46 | 0.06 (0.04,0.08) | 49 | 0.05 (0.04,0.07) |
| B*44:02 | 102 | 0.06 (0.05,0.07) | 87 | 0.09 (0.07,0.11) | 14 | 0.02(0.01,0.04) | 51 | 0.07 (0.05,0.09) | 51 | 0.05 (0.04,0.07) |
| B*44:03 | 80 | 0.05 (0.04,0.06) | 45 | 0.04 (0.03,0.06) | 36 | 0.06(0.04,0.08) | 28 | 0.04 (0.02,0.05) | 52 | 0.06 (0.04,0.07) |
| B*53:01 | 77 | 0.05 (0.04,0.06) | 10 | 0.01 (0.00,0.02) | 66 | 0.10(0.08,0.13) | 22 | 0.03 (0.02,0.04) | 55 | 0.06 (0.04,0.08) |
| C*03:04 | 104 | 0.06 (0.05,0.07) | 55 | 0.05 (0.04,0.07) | 41 | 0.06(0.05,0.09) | 41 | 0.05 (0.04,0.07) | 63 | 0.07 (0.05,0.09) |
| C*04:01 | 233 | 0.14 (0.12,0.15) | 124 | 0.12 (0.10,0.15) | 107 | 0.17(0.14,0.20) | 98 | 0.13 (0.10,0.15) | 135 | 0.15 (0.12,0.17) |
| C*05:01 | 106 | 0.06 (0.05,0.07) | 86 | 0.09 (0.07,0.10) | 19 | 0.03(0.02,0.05) | 55 | 0.07 (0.05,0.09) | 51 | 0.05 (0.04,0.07) |
| C*06:02 | 115 | 0.07 (0.06,0.08) | 83 | 0.08 (0.07,0.10) | 29 | 0.05(0.03,0.06) | 65 | 0.08 (0.07,0.11) | 49 | 0.05 (0.04,0.07) |
| C*07:01 | 203 | 0.12 (0.10,0.14) | 154 | 0.15 (0.13,0.18) | 47 | 0.07(0.05,0.10) | 98 | 0.13 (0.10,0.15) | 105 | 0.11 (0.09,0.14) |
| C*07:02 | 175 | 0.10 (0.09,0.12) | 118 | 0.12 (0.10,0.14) | 46 | 0.07(0.05,0.10) | 97 | 0.13 (0.10,0.15) | 78 | 0.08 (0.07,0.10) |