Table 3:

Association of AD and HLA Class I allelic variation presented as odds ratios with 95% confidence intervals (OR > 1 represents increased risk). ORs presented for the full cohort. The full cohort adjusted by ancestry and for just those of European or African ancestry. The p-value correction (in manuscript) is based on analyses per gene; HLA-A 4, HLA-B 6 and HLA-C 6.

Allele	OR	p-value	Adjusted OR	European Ancestry	African Ancestry
A*01:01	0.46 (0.33, 0.63)	1.35e-06	0.55(0.40, 0.77)	0.54 (0.37, 0.77)	0.54(0.22, 1.35)
A*02:01	0.71 (0.56, 0.90)	.0049846	0.82(0.63, 1.06)	0.94 (0.70, 1.24)	0.64(0.38, 1.11)
A*03:01	0.92 (0.70, 1.21)	.5642952	1.05(0.79, 1.41)	0.94 (0.67, 1.31)	1.31(0.76, 2.26)
A*24:02	0.75 (0.51, 1.20)	.1549402	0.89(0.59, 1.34)	1.09 (0.70, 1.71)	0.13(0.04, 0.47)
B*07:02	0.60 (0.43, 0.82)	.0015001	0.56(0.40, 0.78)	0.48 (0.31, 0.75)	0.77(0.44, 1.34)
B*08:01	0.84 (0.59, 1.20)	.3335906	1.03(0.71, 1.50)	1.02 (0.68, 1.52)	1.03(0.43, 2.46)
B*35:01	0.88 (0.59, 1.34)	.5634918	0.88(0.57, 1.35)	0.62 (0.34, 1.12)	1.36(0.70, 2.66)
B*44:02	0.83 (0.57, 1.23)	.3660473	1.06(0.71, 1.60)	1.10 (0.71, 1.69)	0.77(0.28, 2.13)
B*44:03	1.60 (1.00, 2.58)	.0516518	1.62(0.99, 2.66)	1.52 (0.82, 2.81)	2.06(0.92, 4.63)
B*53:01	1.98 (1.22, 3.22)	.005361	1.43(0.87, 2.36)	1.77 (0.49, 6.36)	1.51(0.88, 2.60)
C*03:04	1.31 (0.87, 1.98)	.1919211	1.23(0.80, 1.90)	1.35 (0.77, 2.36)	1.10(0.57, 2.11)
C*04:01	1.17 (0.89, 1.54)	.2586665	1.12(0.84, 1.50)	0.80 (0.55, 1.16)	2.10(1.28, 3.42)
C*05:01	0.77 (0.52, 1.13)	.1841949	0.97(0.64, 1.45)	0.92 (0.59, 1.43)	0.97(0.37, 2.54)
C*06:02	0.60 (0.41, 0.89)	.0109947	0.66(0.44, 0.98)	0.66 (0.41, 1.06)	0.80(0.38, 1.69)
C*07:01	0.89 (0.67, 1.18)	.4195639	1.06(0.78, 1.42)	1.06 (0.76, 1.47)	1.00(0.53, 1.88)
C*07:02	0.66 (0.49, 0.90)	.0084513	0.66(0.48, 0.91)	0.58 (0.39, 0.86)	0.88(0.48, 1.60)