. Author manuscript; available in PMC: 2022 Jul 1.

Published in final edited form as: Am J Kidney Dis. 2021 Jan 1;78(1):75–84.e1. doi: 10.1053/j.ajkd.2020.11.014

Table 5:

Harrell’s C statistic for clinical models ± biomarkers in predicting KFRT.

Model	Harrell’s C Statistic (95% CI)	Difference in C Statistic (95% CI)
Clinical Model: adjusted for age, sex, systolic BP, BMI, current smoking, GFR, and log₂(urine PCR)	0.849 (0.820, 0.878)	Ref
Clinical Model + log₂(sTNFR1)	0.860 (0.833, 0.887)	0.011 (0.001, 0.021)
Clinical Model + log₂(sTNFR1) + log₂(TNF-α)	0.860 (0.834, 0.887)	0.011 (0.002, 0.021)
Clinical Model + log₂(sTNFR1) + log₂(suPAR)	0.860 (0.833, 0.887)	0.011 (0.001, 0.021)
Clinical Model + log₂(sTNFR1) + log₂(TNF-α) + log₂(suPAR)	0.860 (0.833, 0.887)	0.011 (0.001, 0.021)

Abbreviations: BP=blood pressure; GFR=glomerular filtration rate; PCR=protein-to-creatinine ratio; sTNFR1=soluble tumor necrosis factor receptor 1; TNF-α=tumor necrosis factor alpha; IFN-γ=interferon gamma; suPAR=soluble urokinase-type plasminogen activator receptor.