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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Drug Deliv Transl Res. 2021 Mar 12;11(4):1675–1688. doi: 10.1007/s13346-021-00955-0

Figure 4.

Figure 4.

(A) Colony stimulating factor-1 receptor inhibition (CSF1R inh.) mitigated fibrotic overgrowth on intraperitoneally injected alginate spheres in mice as compared to vehicle only and CXCL13 neutralized wild type mice. (B) Histological examination of intraperitoneal alginate spheres in non-human primates. (C) Macrophage populations (green) and fibrosis associated α-smooth muscle actin (red) around explanted alginate spheres from non-human primates as visualized by confocal imaging. Modified with permission from [113].