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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Drug Deliv Transl Res. 2021 Mar 12;11(4):1675–1688. doi: 10.1007/s13346-021-00955-0

Table 1.

Summary of manufacturing methods, materials and active ingredients used in implants described in section 2.2.12.2.3.

Device Implant material Processing method Active ingredient Clinical application Reference
Prosthetic joint LDPE Compression molding Rifampin, Vancomycin Recurrent PJI prevention [41]
Kirschner Wire PLGA, PCL Electrospinning Vancomycin, Daptomycin, Linezolid, Rifampin Preventing infection after bone fractures [44]
Ureteral stent Biosoft® polymer blend - Tachyplesin III Preventing ureteral stent infection [51]
Device coating Poly(HPMA) Surface-initiated atom transfer radical polymerization None Urinary catheter coating to prevent biofilm formation [52]
Device coating Biosoft® polymer blend Dip coating Vancomycin, BMAP-28 Ureteral stent coating to prevent bacterial adhesion [53]
Antibacterial suture Nylon, Polyglactin High temperature extrusion Triclosan Preventing post-operative infection-general surgery [57]
Antibacterial suture PCL,PEG Electrospinning Levofloxacin Preventing post-operative infection-ophthalmic surgery [59]
Antibacterial suture PCL Electrospinning Levofloxacin Preventing post-operative infection-ophthalmic surgery [65]