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Initial screening of peptides at a concentration of 5 μM (single dose duplicate).
| % Enzyme Activity (relative to DMSO controls) | ||||
|---|---|---|---|---|
| [WR]5 | [WR]9 | [R6K]W6 | [R5K]W7 | |
| Abl1 | 49.2 | 7.0 | 18.4 | 17.1 |
| c-Kit | 41.0 | 38.8 | 83.1 | 88.0 |
| c-Src | 6.2 | 1.4 | 141.2 | 95.1 |
| Cdk2/cyclin A1 | 33.9 | 5.6 | 5.9 | 7.0 |
| Csk | 11.3 | 7.7 | 91.8 | 69.7 |
| EGFR | 69.1 | 72.6 | 126.6 | 119.0 |
| Lck | 32.2 | 18.1 | 88.0 | 89.7 |
| mTOR/FRAP 1 | 146.9 | 133.3 | 152.9 | 111.9 |
| P38a/MAPK14 | 92.0 | 61.0 | 51.4 | 64.2 |
| PKCa | 8.9 | 5.0 | 6.8 | 15.8 |
