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. Author manuscript; available in PMC: 2022 Jun 28.
Published in final edited form as: Analyst. 2021 Jun 28;146(13):4135–4145. doi: 10.1039/d1an00060h

Fig. 6. 3D multi-channel prediction of plaque-bearing hippocampus from two sets (top and bottom) of VISTA images.

Fig. 6

(A) VISTA images. (B) Four-channel overlay for v-DAPI (cyan, nuclei), v-Congo red (green, for plaque core), v-GLUT1 (red, blood vessels), and v-Peripheral plaque (white) by U-net predicted high-resolution segmentation of the VISTA images in (A). (C) 6-color tandem fluorescence image of MBP (magenta, myelin basic protein) and GFAP (yellow, Glial fibrillary acidic protein) with 4-channel VISTA predictions. Scale bars: 30 μm.