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. 2021 Jun 28;4:805. doi: 10.1038/s42003-021-02336-2

Fig. 4. Flupyradifurone (FPF) time-reinforced toxicity assessment.

Fig. 4

There is no evidence of time-reinforced toxicity of FPF in honey bees, as its toxicity (estimated global regression of the Lethal Daily Dose causing 50% mortality, LDD50; black solid line) over time (days) was not significantly different from Haber’s rule (random slope mixed model; dashed grey line with a slope of −1). We display separate regression lines, using different colours, for each laboratory. Further details are available in the Supplementary Methods and Results.